Delivering a disease-modifying treatment for Huntington’s disease

Huntington's disease (HD) is an incurable genetic neurodegenerative disorder that leads to motor and cognitive decline. It is caused by an expanded polyglutamine tract within the Huntingtin (HTT) gene, which translates into a toxic mutant HTT protein. Although no cure has yet been discovered, n...

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Detalhes bibliográficos
Autor principal: Godinho, Bruno M. C. (author)
Outros Autores: Malhotra, Meenakshi (author), O’Driscoll, Caitriona M. (author), Cryan, John F. (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Huntington's disease
Neurodegenerative disorder
Huntingtin gene
RNA interference
DNA enzymes
Texto completo:http://hdl.handle.net/10400.21/3848
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/3848

Texto Completo

http://hdl.handle.net/10400.21/3848

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