Dhvar5 antimicrobial peptide (AMP) chemoselective covalent immobilization results on higher antiadherence effect than simple physical adsorption

Bacterial colonization and subsequent biofilm formation is still one of the major problems associated with medical devices. Antimicrobial peptides (AMP) immobilization onto biomaterials surface is a promising strategy to avoid bacterial colonization. However, a correct peptide orientation and exposu...

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Detalhes bibliográficos
Autor principal: Costa, FM (author)
Outros Autores: Maia, SR (author), Gomes, PA (author), Martins, MCL (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Adsorption
Anti-Infective Agents/chemistry
Antimicrobial Cationic Peptides/chemistry
Bacteria/drug effects
Bacterial Adhesion
Bacterial Proteins/chemistry
Chitosan/chemistry
Coated Materials Biocompatible/chemistry
Histatins/chemistry
Methicillin-Resistant Staphylococcus aureus/drug effects
Microbial Sensitivity Tests
Protein Structure, Tertiary
Spectroscopy Fourier Transform Infrared
Surface Properties
Water
Texto completo:http://hdl.handle.net/10216/110358
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/110358

Texto Completo

http://hdl.handle.net/10216/110358

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