miR-181a negatively regulates human γδ T cell differentiation into anti-tumor effectors

Cytotoxicity and IFN-γ production by human γδ T cells underlie their potent anti-tumor functions. importantly, we have previously shown that ex vivo-isolated γδ thymocytes produced negligible IFN-γ and lacked cytolytic activity against leukemia cells but could acquire those properties upon stimulati...

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Detalhes bibliográficos
Autor principal: Gordino, Gisela (author)
Outros Autores: Pereira, Sara (author), Gomes, Anita Q. (author), silva-Santos, Bruno (author), Ribot, Julie (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10400.21/11308
País:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/11308