Synthesis of novel beta-substituted alpha,beta-dehydroamino acid derivatives

beta-Substituted alpha,beta-dehydroamino acids are synthesised in high yields by a Michael addition of heterocyclic nucleophiles to the methyl esters of N-tert-butyloxycarbonyl,N-(4-toluenesulfonyl)dehydroamino acids, followed by a base-induced elimination of the 4-toluenesulfonyl group with regener...

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Bibliographic Details
Main Author: Ferreira, Paula M. T. (author)
Other Authors: Maia, Hernâni Lopes Silva (author), Monteiro, Luís S. (author), Sacramento, Joana (author)
Format: article
Language:eng
Published: 2000
Subjects:
alpha,beta-dehydroamino acids
beta-substituted alanines
beta-substituted alpha,beta-dehydroamino acids
α,β-Dehydroamino acids
β-Substituted alanines
β-Substituted α,β-dehydroamino acids
Science & Technology
Online Access:http://hdl.handle.net/1822/72912
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/72912

Internet

http://hdl.handle.net/1822/72912

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