Role of adenosine on the resistance to temozolomide anti-tumor agent in glioblastoma

Glioblastoma is a primary brain tumor of glial cells with a high incidence in adults and is one of the most abundant brain cancer pathologies. This type of tumor is associated with high genomic instability caused by global hypomethylation of the DNA, that induces activation of oncogenes, loss of imp...

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Bibliographic Details
Main Author: Nogueira, Vanda Cristina Simões (author)
Format: masterThesis
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.6/10537
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/10537