Molecular mechanisms of the metabolite 4-hydroxytamoxifen of the anticancer drug tamoxifen: use of a model microorganism
A strain of the thermophilic eubacterium Bacillus stearothermophilus was used as a model system to identify membrane mediated cytotoxic effects of 4-hydroxytamoxifen, following previous studies with tamoxifen. With this experimental approach we attempted to further clarify tamoxifen and 4-hydroxytam...
Autor principal: | |
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Outros Autores: | , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2003
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10316/5777 |
País: | Portugal |
Oai: | oai:estudogeral.sib.uc.pt:10316/5777 |