Molecular mechanisms of the metabolite 4-hydroxytamoxifen of the anticancer drug tamoxifen: use of a model microorganism
A strain of the thermophilic eubacterium Bacillus stearothermophilus was used as a model system to identify membrane mediated cytotoxic effects of 4-hydroxytamoxifen, following previous studies with tamoxifen. With this experimental approach we attempted to further clarify tamoxifen and 4-hydroxytam...
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| Other Authors: | , , , |
| Format: | article |
| Language: | eng |
| Published: |
2003
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10316/5777 |
| Country: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/5777 |