Evaluation of combined cytotoxic effects of effects of ochratoxin A and fumonisina B1 in human liver and renal cells

Mycotoxins are fungal food contaminants with potential to cause severe acute and chronic conditions1. Therefore, food contamination with mycotoxins such as ochratoxin A (OTA) and fumonisin B1 (FB1) causes great concern. Previous studies addressed the co-occurrence of these toxins in foods2, however...

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Bibliographic Details
Main Author: Tavares, A.M. (author)
Other Authors: Mendonça, I. (author), Alvito, Paula (author), Loureiro, S. (author), Louro, Henriqueta (author), Silva, Maria (author)
Format: other
Language:por
Published: 2015
Subjects:
Genotoxicidade Ambiental
Mycotoxins
Mixtures Toxicity
Genotoxicity
Online Access:http://hdl.handle.net/10400.18/3073
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3073
Description
Summary:Mycotoxins are fungal food contaminants with potential to cause severe acute and chronic conditions1. Therefore, food contamination with mycotoxins such as ochratoxin A (OTA) and fumonisin B1 (FB1) causes great concern. Previous studies addressed the co-occurrence of these toxins in foods2, however there is little knowledge on their combined cytotoxic effects. In the present study we aimed to evaluate the cytotoxic effects of mixtures of OTA and FB1 in two human-derived cell lines.

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