Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits viral replication

Human immunodeficiency virus type 1 (HIV-1) encoded Vif protein is important for viral replication and infectivity. Therefore, Vif is considered to be an important alternative therapeutic target for inhibition of viral infectivity at the level of viral as

Bibliographic Details
Main Author: Goncalves, J (author)
Other Authors: Silva, F (author), Freitas-Vieira, A (author), Santa-Marta, M (author), Malho, R (author), Yang, X (author), Gabuzda, D (author), Barbas, C (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21598
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21598
Description
Summary:Human immunodeficiency virus type 1 (HIV-1) encoded Vif protein is important for viral replication and infectivity. Therefore, Vif is considered to be an important alternative therapeutic target for inhibition of viral infectivity at the level of viral as