Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat

Background. Activation of the cysteine protease calpain has been implicated in renal ischemia/reperfusion (I/R) injury. The aim of this study was to investigate the effects of calpain inhibitor-1 (Cal I-1) in an in vivo model of renal I/R injury. Methods. Male Wistar rats were administered (Cal I-1...

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Bibliographic Details
Main Author: Chatterjee, PK (author)
Other Authors: Brown, PAJ (author), Cuzzocrea, S (author), Zacharowski, K (author), Stewart, KN (author), Mota-Filipe, H (author), McDonald, MC (author), Thiemermann, C (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21215
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21215