The potential of 99mTc-PEI-MP for diagnosis and 188Re-PEI-MP for therapy of bladder carcinoma

Introduction: The water-soluble polymer PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) that might be labeled with 188Re and 99mTc presents a strong potential for metabolic radiotherapy and diagnosis, respectively. The aim of this study was to evaluate in vivo the potential...

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Bibliographic Details
Main Author: Ferreira, Sara (author)
Other Authors: Laranjo, Mafalda (author), Abrantes, Ana Margarida (author), Brito, Ana (author), Metello, Luís F. (author), Zeevart, Jan (author), Louw, Werner (author), Dormehl, Irene (author), Botelho, Maria Filomena (author)
Format: other
Language:eng
Published: 2015
Online Access:http://hdl.handle.net/10400.22/6442
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/6442
Description
Summary:Introduction: The water-soluble polymer PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) that might be labeled with 188Re and 99mTc presents a strong potential for metabolic radiotherapy and diagnosis, respectively. The aim of this study was to evaluate in vivo the potential of 188Re-PEI-MP as therapeutic agent for bladder carcinoma and 99mTc-PEI-MP for its diagnosis and follow up

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