Genome-wide shRNA screening identifies genes involved in fulvestrant resistance in breast cancer

Breast cancer accounts as the most prevalent cancer and the leading cause of cancer death worldwide among women. Estrogen is one main factor responsible for tumour growth in breast cancer patients through stimulation of estrogen receptor (ER) signalling. ER positive (ER+) breast cancer patients are...

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Bibliographic Details
Main Author: Ramos, Pedro André Dias (author)
Format: masterThesis
Language:eng
Published: 2016
Subjects:
ER+ breast cancer
Fulvestrant resistance
Genome-wide shRNA screening
HSD17B10
HSPE1
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Online Access:http://hdl.handle.net/10362/19135
Country:Portugal
Oai:oai:run.unl.pt:10362/19135

Internet

http://hdl.handle.net/10362/19135

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