Azabicyclo[3.2.0]heptan-7-ones (carbapenams) from pyrrole

The azabicyclo[3.2.0]heptan-7-ones 4, 10, 16 and 24 have been prepared from pyrrole. The same general approach has been used for all these derivatives; namely, substitution of pyrrole at the 2- and 5-carbon atoms, catalytic hydrogenation to produce pyrrolidine-2-acetic acid derivatives, and cyclisat...

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Bibliographic Details
Main Author: Gilchrist, Thomas L. (author)
Other Authors: Lemos, A. (author), Ottaway, Carol J. (author)
Format: article
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10400.1/935
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/935