In Vitro Evaluation of Novel Reverse Transcriptase Inhibitors TAF (Tenofovir Alafenamide) and OBP-601 (2,3-didehydro-3-deoxy-4-ethynylthymidine) Against Multi-Drug Resistant Primary Isolates of HIV-2

New antiretroviral drugs are needed to treat HIV-2 infected patients failing therapy. Herein, we evaluate the activity of novel reverse transcriptase inhibitors tenofovir alafenamide (TAF) and OBP-601(2,3-didehydro-3-deoxy-4-ethynylthymidine) against primary isolates from HIV-2 infected patients exp...

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Bibliographic Details
Main Author: Bártolo, I (author)
Other Authors: Borrego, P (author), Gomes, P (author), Gonçalves, F (author), Caixas, U (author), Pinto, IV (author), Taveira, N (author)
Format: article
Language:eng
Published: 2018
Subjects:
TDF and OBP-601
Susceptibility to TAF
Resistance Mutations
HIV-2
HSJ MED
Online Access:http://hdl.handle.net/10400.17/3121
Country:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/3121

Internet

http://hdl.handle.net/10400.17/3121

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