Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

Biogenesis of cystic fibrosis transmembrane conductance regulator (CFTR) starts with its cotranslational insertion into the membrane of the endoplasmic reticulum (ER) and core glycosylation. These initial events are followed by a complex succession of steps with the main goal of checking the overall...

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Bibliographic Details
Main Author: Farinha, Carlos (author)
Other Authors: Matos, Paulo (author), Amaral, Margardia (author)
Format: article
Language:eng
Published: 2014
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
Fibrose Quística
Doença Genética
CFTR
Traffic
Rab GTPases
Rho GTPases
Trafficking
Chaperones
Cystic Fibrosis Transmembrane Conductance Regulator
Endocytosis
Endoplasmic Reticulum
Endoplasmic Reticulum Quality Control
Folding
Online Access:http://hdl.handle.net/10400.18/2101
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2101

Internet

http://hdl.handle.net/10400.18/2101

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