Investigation of different hydrogels for nucleus replacement : a biomechanical study

Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surrounding structures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. T...

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Bibliographic Details
Main Author: Reitmaier, Sandra (author)
Other Authors: Wolfram, Uwe (author), Ignatius, Anita (author), Wilke, Hans-Joachim (author), Martín-Martínez, José M. (author), Silva-Correia, Joana (author), Oliveira, Joaquim M. (author), Reis, R. L. (author), Schmidt, Hendrik (author)
Format: conferenceObject
Language:eng
Published: 2012
Subjects:
Hydrogels
IVD
Online Access:http://hdl.handle.net/1822/23950
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/23950
Description
Summary:Hydrogels are considered promising for disc regeneration strategies. However, it is currently unknown whether the destruction of the natural interface between nucleus and surrounding structures caused by nucleotomy and an inadequate annulus closure diminishes the mechanical competence of the disc. To clarify these mechanisms and to evaluate whether hydrogels are able to restore the biomechanical behaviour of the disc a combined in vivo and in vitro and approach was used.

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