IFN-gamma-dependent activation of macrophages during experimental infections by Mycobacterium ulcerans is impaired by the toxin mycolactone

Buruli ulcer, caused by Mycobacterium ulcerans infections, is a necrotizing skin disease whose pathogenesis is associated with the exotoxin mycolactone. Despite the relevance of this emergent disease, little is known on the immune response against the pathogen. Following the recent demonstration of...

ver descrição completa

Detalhes bibliográficos
Autor principal: Torrado, Egídio (author)
Outros Autores: Fraga, Alexandra Gabriel (author), Logarinho, Elsa (author), Martins, Teresa G. (author), Carmona, Jenny A. (author), Gama, José B. (author), Carvalho, Maria A. (author), Proença, M. Fernanda R. P. (author), Castro, Antonio G. (author), Pedrosa, Jorge (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Animals
Bacterial Toxins
Cells, Cultured
Interferon-gamma
Macrolides
Macrophage Activation
Macrophages
Mice
Mycobacterium Infections, Nontuberculous
Mycobacterium ulcerans
Nitric Oxide
Phagosomes
Science & Technology
Texto completo:http://hdl.handle.net/1822/67558
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67558

Texto Completo

http://hdl.handle.net/1822/67558

Registros relacionados