Alginate/Chitosan Nanoparticles are Effective for Oral Insulin Delivery

Abstract Purpose To evaluate the pharmacological activity of insulin-loaded alginate/chitosan nanoparticles following oral dosage in diabetic rats. Methods Nanoparticles were prepared by ionotropic pre-gelation of an alginate core followed by chitosan polyelectrolyte complexation. In vivo activity w...

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Bibliographic Details
Main Author: Sarmento, B. (author)
Other Authors: Ribeiro, A. (author), Veiga, F. (author), Sampaio, P. (author), Neufeld, R. (author), Ferreira, D. (author)
Format: article
Language:eng
Published: 2007
Online Access:http://hdl.handle.net/10316/7951
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/7951

Internet

http://hdl.handle.net/10316/7951

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