Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability

Hexavalent chromium [Cr(VI)] is a well-recognized human lung carcinogen. In order to gain further insight into Cr(VI)-induced carcinogenesis, we have established an adequate in vitro cellular model for the study of this process. To this end, BEAS-2B cells were used. Chronic exposure of cells to 1 mu...

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Bibliographic Details
Main Author: Rodrigues, C. F. D. (author)
Other Authors: Urbano, A. M. (author), Matoso, E. (author), Carreira, I. (author), Almeida, A. (author), Santos, P. (author), Botelho, F. (author), Carvalho, L. (author), Alves, M. (author), Monteiro, C. (author), Costa, A. N. (author), Moreno, V. (author), Alpoim, M. C. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biotechnology & Applied Microbiology
Genetics & Heredity
Toxicology
Online Access:http://hdl.handle.net/10451/21034
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21034

Internet

http://hdl.handle.net/10451/21034

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