Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus

ATP is released in a vesicular manner from nerve terminals mainly at higher stimulation frequencies. There is a robust expression of ATP (P2) receptors in the brain, but their role is primarily unknown. We report that ATP analogs biphasically modulate the evoked release of glutamate from purified ne...

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Bibliographic Details
Main Author: Rodrigues, Ricardo J. (author)
Other Authors: Almeida, Teresa (author), Richardson, Peter J. (author), Oliveira, Catarina R. (author), Cunha, Rodrigo A. (author)
Format: article
Language:eng
Published: 2005
Subjects:
ATP
P2X receptors
P2Y receptors
Glutamate release
Nerve terminals
Rat hippocampus
Online Access:http://hdl.handle.net/10316/12622
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/12622

Internet

http://hdl.handle.net/10316/12622

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