Nevirapine biotransformation insights

Funding: This work was supported by FCT (Portugal) through the research grant PTDC/MED-TOX/29183/2017. Acknowledgments: The authors thank ECBio S.A. for providing the hnMSCs and F.A. Beland (NCTR, Jefferson, AR, USA) for the kind donation of nevirapine. FCT (UID/DTP/04138/2019, UID/QUI/00100/2019, R...

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Detalhes bibliográficos
Autor principal: Cipriano, Madalena (author)
Outros Autores: Pinheiro, Pedro F. (author), Sequeira, Catarina O. (author), Rodrigues, Joana S. (author), Oliveira, Nuno G. (author), Antunes, Alexandra M.M. (author), Castro, Matilde (author), Marques, M. Matilde (author), Pereira, Sofia A. (author), Miranda, Joana P. (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
3D culture
Glutathione
Hepatocytes
Metabolism
Nevirapine
Stem cells
Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
Texto completo:http://hdl.handle.net/10362/99536
País:Portugal
Oai:oai:run.unl.pt:10362/99536
Descrição
Resumo:Funding: This work was supported by FCT (Portugal) through the research grant PTDC/MED-TOX/29183/2017. Acknowledgments: The authors thank ECBio S.A. for providing the hnMSCs and F.A. Beland (NCTR, Jefferson, AR, USA) for the kind donation of nevirapine. FCT (UID/DTP/04138/2019, UID/QUI/00100/2019, RECI/QEQ-MED/0330/2012, SFRH/BD/144130/2019 to J.S.R., SFRH/BD/110945/2015 to P.F.P. and CEECIND/02001/2017 to A.M.M.A) are also acknowledged.

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