Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase

Members of the WNK (with-no-lysine [K]) subfamily of protein kinases regulate various ion channels involved in sodium, potassium, and chloride homeostasis by either inducing their phosphorylation or regulating the number of channel proteins expressed at the cell surface. Here, we describe findings d...

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Bibliographic Details
Main Author: Mendes, Ana Isabel (author)
Other Authors: Matos, Paulo (author), Moniz, Sónia (author), Luz, Simão (author), Amaral, Margarida D. (author), Farinha, Carlos M. (author), Jordan, Peter (author)
Format: article
Language:eng
Published: 2011
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
Protein kinase
Cystic Fibrosis
Spleen tyrosine kinase
WNK
Cell surface protein
Membrane traffic
Online Access:http://hdl.handle.net/10400.18/242
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/242

Internet

http://hdl.handle.net/10400.18/242

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