Bi-layered self-emulsifying pellets prepared by co-extrusion and spheronization

The aim of this work was to produce by co-extrusion-spheronization pellets with two cohesive layers, one of them containing a self-emulsifying system for vinpocetine, a poorly water soluble model drug. Two layers were prepared: an inert layer of microcrystalline cellulose, lactose and water and a se...

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Bibliographic Details
Main Author: Iosio, Tamara (author)
Other Authors: Voinovich, Dario (author), Grassi, Mario (author), Pinto, Joao F. (author), Perissutti, Beatrice (author), Zacchigna, Marina (author), Quintavalle, Ugo (author), Serdoz, Francesca (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21259
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21259