OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells
Intestinal metaplasia (IM) is a preneoplastic lesion of the stomach in which there is transdifferentiation of the gastric mucosa to an intestinal phenotype. The caudal-related homeobox gene CDX2 encodes an intestine-specific transcription factor crucial for the regulation of proliferation and differ...
Main Author: | |
---|---|
Other Authors: | , , , , , , , , |
Format: | article |
Language: | eng |
Published: |
2005
|
Subjects: | |
Online Access: | https://hdl.handle.net/10216/1891 |
Country: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/1891 |