Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

Chemokines are involved in the control of dendritic cell (DC) trafficking, which is critical for the immune response, namely in allergic contact dermatitis (ACD). In this work, we investigated by flow cytometry the effect of the contact sensitizers 2,4-dinitrofluorobenzene (DNFB), 1,4-phenylenediami...

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Detalhes bibliográficos
Autor principal: Cruz, MT (author)
Outros Autores: Gonçalo, Margarida (author), Paiva, A (author), Morgado, JM (author), Figueiredo, A (author), Duarte, CB (author), Lopes, MC (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Texto completo:http://hdl.handle.net/10400.4/753
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/753