Pseudotyping retrovirus like particles vaccine candidates with Hepatitis C virus envelope protein E2 requires the cellular expression of CD81

Hepatitis C virus (HCV) infects 3% of world population being responsible for nearly half a million deaths annually urging the need for a prophylactic vaccine. Retrovirus like particles are commonly used scaffolds for antigens presentation being the core of diverse vaccine candidates. The immunogenic...

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Bibliographic Details
Main Author: Soares, Hugo R. (author)
Other Authors: Castro, Rute (author), Tomás, Hélio A. (author), Carrondo, Manuel J.T. (author), Alves, Paula M. (author), Coroadinha, Ana S. (author)
Format: article
Language:eng
Published: 2020
Subjects:
CD81
E1
E2
HCV
Retrovirus
Transport
Biophysics
Applied Microbiology and Biotechnology
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/96253
Country:Portugal
Oai:oai:run.unl.pt:10362/96253

Internet

http://hdl.handle.net/10362/96253

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