Prediction of the in vitro intrinsic clearance determined in suspensions of human hepatocytes by using artificial neural networks

Use of in vitro suspensions of human hepatocytes is currently accepted as one of the most promising tools for prediction of metabolic clearance in new drugs. The possibility of creating computational models based on this data may potentiate the early selection process of new drugs. We present an art...

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Detalhes bibliográficos
Autor principal: Paixão, Paulo (author)
Outros Autores: Gouveia, Luís F. (author), Morais, José A. G. (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Texto completo:http://hdl.handle.net/10451/8513
País:Portugal
Oai:oai:repositorio.ul.pt:10451/8513