Wortmannin enhances the induction of micronuclei by low and high LET radiation

In mammalian cells, the repair of DNA double-strand breaks (DSBs) is mainly mediated by DNA non-homologous end joining. DNA-dependent protein kinase (DNA-PK), a nuclear serine-threonine kinase and a member of the phosphaditylinositol-3 kinase-related kinase family that is activated by DSBs, is a key...

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Bibliographic Details
Main Author: Oliveira, NG (author)
Other Authors: Castro, M (author), Rodrigues, AS (author), Goncalves, IC (author), Gil, OM (author), Fernandes, AP (author), Toscano-Rico, JM (author), Rueff, J (author)
Format: article
Language:eng
Published: 2015
Subjects:
Genetics & Heredity
Toxicology
Online Access:http://hdl.handle.net/10451/21482
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21482

Internet

http://hdl.handle.net/10451/21482

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