Application of locked nucleic acid-based probes in fluorescence in situ hybridization

Fluorescence in situ hybridization (FISH) employing nucleic acid mimics as probes is becoming an emerging molecular tool in the microbiology area for the detection and visualization of microorganisms. However, the impact that locked nucleic acid (LNA) and 2'-O-methyl (2'-OMe) RNA modificat...

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Detalhes bibliográficos
Autor principal: Sílvia Fontenete (author)
Outros Autores: Daniel Carvalho (author), Nuno Guimarães (author), Pedro Madureira (author), Céu Figueiredo (author), Jesper Wengel (author), Nuno Filipe Azevedo (author)
Formato: article
Idioma:eng
Publicado em: 2016
Texto completo:https://hdl.handle.net/10216/103061
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/103061