Current pharmacotherapy of overactive bladder

ABSTRACT Overactive bladder is a symptom complex consisting of bothersome storage urinary symptoms that is highly prevalent among both sexes and has a significant impact on quality of life. Various antimuscarinic agents and the beta-3 agonists mirabegron and vibegron are currently available for the...

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Bibliographic Details
Main Author: Kreydin,Evgenyi I. (author)
Other Authors: Gomes,Cristiano M. (author), Cruz,Francisco (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382021000601091
Country:Brazil
Oai:oai:scielo:S1677-55382021000601091
Description
Summary:ABSTRACT Overactive bladder is a symptom complex consisting of bothersome storage urinary symptoms that is highly prevalent among both sexes and has a significant impact on quality of life. Various antimuscarinic agents and the beta-3 agonists mirabegron and vibegron are currently available for the treatment of OAB. Each drug has specific pharmacologic properties, dosing schedule and tolerability profile, making it essential to individualize the medical treatment for the patient's characteristics and expectations. In this manuscript, we review the most important factors involved in the contemporary pharmacological treatment of OAB.