Genomic rearrangements in BRCA1 and BRCA2: a literature review

Women with mutations in the breast cancer genes BRCA1 or BRCA2 have an increased lifetime risk of developing breast, ovarian and other BRCA-associated cancers. However, the number of detected germline mutations in families with hereditary breast and ovarian cancer (HBOC) syndrome is lower than expec...

Full description

Bibliographic Details
Main Author: Ewald,Ingrid Petroni (author)
Other Authors: Ribeiro,Patricia Lisboa Izetti (author), Palmero,Edenir Inêz (author), Cossio,Silvia Liliana (author), Giugliani,Roberto (author), Ashton-Prolla,Patricia (author)
Format: article
Language:eng
Published: 2009
Subjects:
BRCA1
BRCA2
breast cancer
genomic rearrangements
MLPA
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000300003
Country:Brazil
Oai:oai:scielo:S1415-47572009000300003

Internet

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000300003

Similar Items