The effects of old and recent migration waves in the distribution of HBB*S globin gene haplotypes

Abstract Sickle cell hemoglobin is the result of a mutation at the sixth amino acid position of the beta (β) globin chain. The HBB*S gene is in linkage disequilibrium with five main haplotypes in the β-globin-like gene cluster named according to their ethnic and geographic origins: Bantu (CAR), Beni...

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Bibliographic Details
Main Author: Lindenau,Juliana D. (author)
Other Authors: Wagner,Sandrine C. (author), Castro,Simone M. de (author), Hutz,Mara H. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400515
Country:Brazil
Oai:oai:scielo:S1415-47572016000400515