Acute stress-induced antinociception is cGMP-dependent but heme oxygenase-independent

Endogenous carbon monoxide (CO), which is produced by the enzyme heme oxygenase (HO), participates as a neuromodulator in physiological processes such as thermoregulation and nociception by stimulating the formation of 3′,5′-cyclic guanosine monophosphate (cGMP). In particular, the acute physical re...

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Bibliographic Details
Main Author: Carvalho-Costa,P.G. (author)
Other Authors: Branco,L.G.S. (author), Leite-Panissi,C.R.A. (author)
Format: article
Language:eng
Published: 2014
Subjects:
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001201057
Country:Brazil
Oai:oai:scielo:S0100-879X2014001201057