Effects of ketamine administration on mTOR and reticulum stress signaling pathways in the brain after the infusion of rapamycin into prefrontal cortex

Recent studies show that activation of the mTOR signaling pathway is required for the rapid antide- pressant actions of glutamate N-methyl-D-aspartate (NMDA) receptor antagonists. A relationship be- tween mTOR kinase and the endoplasmic reticulum (ER) stress pathway, also known as the unfolded prote...

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Bibliographic Details
Main Author: Abelaira, Helena M. (author)
Other Authors: Réus, Gislaine Z. (author), Ignácio, Zuleide M. (author), Santos, Maria Augusta B. dos (author), Moura, Airam B. de (author), Matos, Danyela (author), Demo, Júlia P. (author), Silva, Júlia B.I. da (author), Michels, Monique (author), Abatti, Mariane A (author), Sonai, Beatriz (author), Pizzol, Felipe Dal (author), Carvalho, André F. (author), Quevedo, João (author)
Format: article
Language:eng
Published: 2017
Subjects:
Ketamina
Ketamine
Transtorno Depressivo Maior
Depressive Disorder, Major
Online Access:http://www.repositorio.ufc.br/handle/riufc/24810
Country:Brazil
Oai:oai:www.repositorio.ufc.br:riufc/24810

Internet

http://www.repositorio.ufc.br/handle/riufc/24810

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