Alpha-1 antitrypsin gene polymorphism in Chronic Obstructive Pulmonary Disease (COPD)

Alpha-1-antitrypsin (AAT) plays an important role in the pathogenesis of emphysema, the pathological lesion underlying the majority of the manifestations of Chronic Obstructive Pulmonary Disease (COPD). In this study we tested the hypothesis that common AAT polymorphisms influence the risk of develo...

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Bibliographic Details
Main Author: Denden,Sabri (author)
Other Authors: Khelil,Amel Haj (author), Knani,Jalel (author), Lakhdar,Ramzi (author), Perrin,Pascale (author), Lefranc,Gérard (author), Chibani,Jemni Ben (author)
Format: article
Language:eng
Published: 2010
Subjects:
alpha-1 antitrypsin
SERPINA1 polymorphisms
COPD
emphysema
lung function
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100006
Country:Brazil
Oai:oai:scielo:S1415-47572010000100006

Internet

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100006

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