Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and management
Ovarian cancer patients with homologous recombination deficiencies exhibit specific clinical behaviors, and improved responses to treatments, such as platinum-based chemotherapy and poly (ADP-ribose) polymerase (PARP) inhibitors, have been observed. Germline mutations in the BRCA 1/2 genes are the m...
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| Other Authors: | , , |
| Format: | article |
| Language: | eng |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://doi.org/10.6061/clinics/2018/e450s |
| Country: | Brazil |
| Oai: | oai:revistas.usp.br:article/154751 |