Polyketides from the marine sponge Plakortis angulospiculatus

Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanyli...

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Detalhes bibliográficos
Autor principal: Epifanio,Rosângela de A. (author)
Outros Autores: Pinheiro,Leandro S. (author), Alves,Natalia C. (author)
Formato: article
Idioma:eng
Publicado em: 2005
Assuntos:
Texto completo:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000800010
País:Brasil
Oai:oai:scielo:S0103-50532005000800010
Descrição
Resumo:Organic extracts of the marine sponge Plakortis angulospiculatus were studied from two different collections from Pernambuco State, Brazil. Bioautography with opportunistic marine pathogens, with results from the brine shrimp lethality assay, were used to guide the purification of the known furanylidenic methyl ester 1 and two new derivatives 2 and 3. The structures were elucidated by spectroscopic methods and by selective reduction of 3 into 2.