Alternagin-C, a disintegrin-like protein from the venom of Bothrops alternatus, modulates alpha2ß1 integrin-mediated cell adhesion, migration and proliferation

The alpha2ß1 integrin is a major collagen receptor that plays an essential role in the adhesion of normal and tumor cells to the extracellular matrix. Alternagin-C (ALT-C), a disintegrin-like protein purified from the venom of the Brazilian snake Bothrops alternatus, competitively interacts with the...

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Bibliographic Details
Main Author: Selistre-de-Araujo,H.S. (author)
Other Authors: Cominetti,M.R. (author), Terruggi,C.H.B. (author), Mariano-Oliveira,A. (author), De Freitas,M.S. (author), Crepin,M. (author), Figueiredo,C.C. (author), Morandi,V. (author)
Format: article
Language:eng
Published: 2005
Subjects:
alpha2ß1 integrin
Disintegrin
Snake venom
Adhesion
Gene expression
Extracellular matrix
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000007
Country:Brazil
Oai:oai:scielo:S0100-879X2005001000007

Internet

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000007

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