Diagnosis of alpha-1-antitrypsin deficiency by DNA analysis of children with liver disease

Background - Alpha-1-antitrypsin deficiency is a genetic disorder which is transmitted in a co-dominant, autosomal form. Alpha-1-antitrypsin deficiency affects mainly the lungs and the liver leading, in the latter case, to neonatal cholestasis, chronic hepatitis or cirrhosis. A precise diagnosis of...

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Bibliographic Details
Main Author: De TOMMASO,Adriana Maria Alves (author)
Other Authors: ROSSI,Cláudio Lúcio (author), ESCANHOELA,Cecília Amélia Fazzio (author), SERRA,Heliane Guerra (author), BERTUZZO,Carmen Sílvia (author), HESSEL,Gabriel (author)
Format: article
Language:eng
Published: 2001
Subjects:
Alpha-1-antitrypsin deficiency
Molecular diagnosis
Liver biopsy
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032001000100012
Country:Brazil
Oai:oai:scielo:S0004-28032001000100012

Internet

http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032001000100012

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