Paclitaxel reduz o crescimento tumoral através da reprogramação de macrófagos associados ao tumor para o perfil M1 via TLR4
Paclitaxel (PCX) is an antineoplastic agent widely used to treat several solid tumor types. The primary mechanism of action of this drug is based on microtubule stabilization and induction of mitotic arrest leading to cells that proliferate rapidly to apoptosis. Here, was investigated whether PCX co...
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| Format: | doctoralThesis |
| Language: | por |
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2018
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| Online Access: | http://www.repositorio.ufc.br/handle/riufc/34977 |
| Country: | Brazil |
| Oai: | oai:www.repositorio.ufc.br:riufc/34977 |