Paclitaxel reduz o crescimento tumoral através da reprogramação de macrófagos associados ao tumor para o perfil M1 via TLR4

Paclitaxel (PCX) is an antineoplastic agent widely used to treat several solid tumor types. The primary mechanism of action of this drug is based on microtubule stabilization and induction of mitotic arrest leading to cells that proliferate rapidly to apoptosis. Here, was investigated whether PCX co...

ver descrição completa

Detalhes bibliográficos
Autor principal: Wanderley, Carlos Wagner de Souza (author)
Formato: doctoralThesis
Idioma:por
Publicado em: 2018
Assuntos:
Texto completo:http://www.repositorio.ufc.br/handle/riufc/34977
País:Brasil
Oai:oai:www.repositorio.ufc.br:riufc/34977