Use of signal thresholds to determine significant changes in microarray data analyses

The use of a constant fold-change to determine significant changes in gene expression has been widely accepted for its intuition and ease of use in microarray data analysis, but this concept has been increasingly criticized because it does not reflect signal intensity and can result in a substantial...

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Bibliographic Details
Main Author: Xinmin,Li (author)
Other Authors: Kim,Jaejung (author), Zhou,Jian (author), Gu,Weikuan (author), Quigg,Richard (author)
Format: article
Language:eng
Published: 2005
Subjects:
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000200002
Country:Brazil
Oai:oai:scielo:S1415-47572005000200002